SCHEMBL29929613

SCHEMBL29929613

O=C(Nc1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 3/20 0.78
JAK1 P23458 3/20 0.78
TYK2 P29597 2/20 0.78
ALDH1A1 P00352 3/20 0.74
LMNA P02545 1/20 0.74
POLB P06746 1/20 0.74
TAS1R3 Q7RTX0 1/20 0.70
TAS1R1 Q7RTX1 1/20 0.70
MEN1 O00255 1/20 0.70
KMT2A Q03164 1/20 0.70
P2RX1 P51575 3/20 0.69
HDAC8 Q9BY41 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
PKM P14618 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
NPC1 O15118 2/20 0.61
HTT P42858 1/20 0.61
RAB9A P51151 1/20 0.61
TMPRSS4 Q9NRS4 2/20 0.60
CYP1A2 P05177 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6005591 0.93 JAK2 (0.69) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL11575341 0.92 ALDH1A1 (0.69) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL10612716 0.91 TMPRSS4 (0.73) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL20601659 0.90 HDAC8 (0.67) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL7329845 0.90 HDAC8 (0.67) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL5336489 0.89 SMN1; SMN2 (0.65) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL11575433 0.87 ALDH1A1 (0.63) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL5341743 0.86 HDAC8 (0.62) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL8316833 0.85 SMN1; SMN2 (0.61) JAK2JAK1TYK2ALDH1A1LMNA
SCHEMBL18160306 0.84 HDAC8 (0.68) JAK2JAK1TYK2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3936038-B1 SIGNAL PROCESSING METHOD, APPARATUS AND NON-TRANSITORY COMPUTER READABLE STORAGE MEDIUM FOR CALCULATING HEART RATES WISTRON CORP (TW) 2026-03-18 EP claimed
EP-4558612-A1 METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS Trailhead Biosystems Inc. (US) 2025-05-28 EP claimed
CN-119585416-A Methods and compositions for generating endothelial cells from pluripotent stem cells 特雷尔赫德生物系统股份有限公司 2025-03-07 CN claimed
CN-119467039-A Double-working-medium circulating power system and control method thereof 贺长宏 2025-02-18 CN claimed
WO-2024020180-A9 METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2025-02-06 WO claimed
CN-118806236-A Non-contact sleep staging method and device based on millimeter wave radar 杭州电子科技大学 2024-10-22 CN claimed
US-20240026301-A1 METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. 2024-01-25 US claimed
WO-2024020180-A1 METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-01-25 WO claimed
CN-122072993-A Rendering method, device and storage medium of three-dimensional model 腾讯数码(深圳)有限公司 2026-05-22 CN disclosed
EP-3936038-B1 SIGNAL PROCESSING METHOD, APPARATUS AND NON-TRANSITORY COMPUTER READABLE STORAGE MEDIUM FOR CALCULATING HEART RATES WISTRON CORP (TW) 2026-03-18 EP disclosed
US-20260049285-A1 3D ISLET FORMATION FROM ENDOCRINE PROGENITOR CELLS SPIBER TECH AB (SE) 2026-02-19 US disclosed
EP-4346928-B1 BIODEGRADABLE TISSUE SCAFFOLD WITH SECONDARY MATRIX TO HOST WEAKLY ADHERENT CELLS US HEALTH (US) 2026-01-14 EP disclosed
US-20250321905-A1 System and Method to Efficiently Assist Time-Synchronous Media Streaming and Remote-Control Applications MICROCHIP TECHNOLOGY INCORPORATED (US) 2025-10-16 US disclosed
US-20250295583-A1 INHALED HEDGEHOG INHIBITORS WBX PHARMA, INC. 2025-09-25 US disclosed
CN-113017589-B Heart rate correction method, system and computer readable medium 纬创资通股份有限公司 2024-06-14 CN disclosed
CN-108469470-B Sample wheel for ultrasonic flaw detection of automatic train wheel line 马鞍山钢铁股份有限公司 2024-03-29 CN disclosed
WO-2024033299-A1 IN VITRO DERIVATION OF PANCREATIC ISLETS FROM HUMAN PLURIPOTENT STEM CELLS SPIBER TECHNOLOGIES AB (SE) 2024-02-15 WO disclosed
WO-2024020180-A1 METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-01-25 WO disclosed
US-20240026301-A1 METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. 2024-01-25 US disclosed
EP-3216125-B1 MULTI-STAGE SLEW RATE CONTROL PROFILING FOR TRANSISTOR DRIVE APPLICATIONS ALLEGRO MICROSYSTEMS LLC (US) 2022-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049285-A1 3D ISLET FORMATION FROM ENDOCRINE PROGENITOR CELLS IAPP, FN1, NES JAK2 2762/4885JAK1 1959/4885TYK2 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.