Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.58 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574525 | 0.86 | GAA (0.58) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL5062623 | 0.80 | PEPD (0.80) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL14324041 | 0.79 | MDM2 (0.61) | NPC1GAAMAPTMEN1LMNA | |
| SCHEMBL13930815 | 0.78 | ALDH1A1 (0.61) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL5933189 | 0.78 | NPC1 (0.61) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL5533028 | 0.78 | KIF11 (0.89) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL13772691 | 0.74 | KIF11 (0.56) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL7663512 | 0.74 | KIF11 (0.66) | KIF11PEPDALDH1A1NPC1GAA | |
| SCHEMBL5999016 | 0.74 | PTPN2 (0.63) | NPC1GAAMAPTGFERMEN1 | |
| SCHEMBL11398244 | 0.74 | CA12 (0.36) | KIF11ALDH1A1NPC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091227-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-4067978-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067977-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067976-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4007173-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |