Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869529 | 0.84 | HTR1A (0.51) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL10241131 | 0.82 | KDM4E (0.56) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL6412098 | 0.81 | DRD4 (0.54) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL29363627 | 0.79 | SIGMAR1 (0.60) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL14601668 | 0.76 | SIGMAR1 (0.60) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL256663 | 0.75 | SIGMAR1 (0.63) | SIGMAR1HTR1AKCNA3 | |
| SCHEMBL5535114 | 0.75 | SIGMAR1 (0.55) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL1061316 | 0.75 | SIGMAR1 (0.55) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL27801629 | 0.74 | KDM4E (0.56) | SIGMAR1HTR1ADRD4DRD2DRD3 | |
| SCHEMBL29188191 | 0.73 | DRD4 (0.67) | SIGMAR1HTR1ADRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470270-A1 | COMPOUNDS FOR TREATMENT OF INFLAMMATION | AnaMar AB (SE) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011012868-A1 | COMPOUNDS FOR TREATMENT OF INFLAMMATION | ANAMAR AB (SE) | 2011-02-03 | — | — | WO | disclosed |
| CN-1053063-A | Quinazoline derivant and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-07-17 | — | — | CN | disclosed |