SCHEMBL10241131

SCHEMBL10241131

CCN1CC=C(c2ccccc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
LMNA P02545 1/20 0.56
ALOX15 P16050 1/20 0.56
SIGMAR1 Q99720 2/20 0.55
HTR1A P08908 1/20 0.55
DRD4 P21917 4/20 0.54
DRD2 P14416 3/20 0.54
DRD3 P35462 2/20 0.54
KCNA3 P22001 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363627 0.86 SIGMAR1 (0.60) SIGMAR1HTR1ADRD4DRD2DRD3
SCHEMBL14144244 0.85 SIGMAR1 (0.54) KDM4ELMNAALOX15SIGMAR1HTR1A
SCHEMBL14601668 0.83 SIGMAR1 (0.60) SIGMAR1HTR1AKCNA3
SCHEMBL25124613 0.82 DRD4 (0.54) KDM4ELMNAALOX15SIGMAR1HTR1A
SCHEMBL7369144 0.82 KDM4E (0.45) KDM4ELMNAALOX15SIGMAR1HTR1A
SCHEMBL14385616 0.82 DRD4 (0.50) KDM4ELMNAALOX15SIGMAR1HTR1A
SCHEMBL7910148 0.82 NPSR1 (0.60) KDM4ELMNAALOX15SIGMAR1DRD2
SCHEMBL25124915 0.82 SIGMAR1 (0.55) KDM4ELMNAALOX15SIGMAR1DRD4
SCHEMBL10241118 0.82 SIGMAR1 (0.57) SIGMAR1HTR1ADRD2
SCHEMBL1157579 0.82 SIGMAR1 (0.49) KDM4ESIGMAR1HTR1ADRD4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240160464-A1 INSTRUCTION SENDING METHOD AND APPARATUS BEIJING BYTEDANCE NETWORK TECHNOLOGY CO., LTD. (CN) 2024-05-16 US claimed
CN-117478625-A High-performance Unikernel virtual machine communication method and device based on vmfunc 浙江大学 2024-01-30 CN claimed
CN-108874500-B Application program safety protection method based on hardware virtualization technology 南京大学 2022-10-18 CN claimed
WO-2022213769-A1 INSTRUCTION SENDING METHOD AND APPARATUS 北京字节跳动网络技术有限公司 2022-10-13 WO claimed
WO-2026100506-A1 DEVICE, METHOD PERFORMED BY DEVICE FOR WIRELESS POWER TRANSMISSION, AND PROGRAM キヤノン株式会社 2026-05-15 WO disclosed
EP-4398138-B1 VIRTUALIZATION-BASED PLATFORM PROTECTION TECHNOLOGY INTEL CORP (US) 2026-04-15 EP disclosed
EP-4315051-B1 APPARATUS AND METHOD FOR MANAGING UNSUPPORTED INSTRUCTION SET ARCHITECTURE (ISA) FEATURES IN A VIRTUALIZED ENVIRONMENT INTEL CORP (US) 2026-04-08 EP disclosed
US-12583882-B2 Equatorially modified polymer linked multimers of guansine-3′, 5′-cyclic monophosphates MIRECA MEDICINES GMBH (DE) 2026-03-24 US disclosed
US-12572378-B2 Secure arbitration mode to build and operate within trust domain extensions INTEL CORPORATION (US) 2026-03-10 US disclosed
US-20260056855-A1 COST REDUCED HIGH RELIABILITY FAULT TOLERANT COMPUTER ARCHITECTURE STRATUS TECHNOLOGIES IRELAND LTD. (IE) 2026-02-26 US disclosed
US-12554657-B2 Virtualization-based platform protection technology INTEL CORPORATION (US) 2026-02-17 US disclosed
US-20250390443-A1 VIRTUALIZATION-BASED PLATFORM PROTECTION TECHNOLOGY INTEL CORPORATION (US) 2025-12-25 US disclosed
US-20100179140-A1 INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORPORATION (US) 2010-07-15 US disclosed
US-20100121049-A1 INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORPORATION (US) 2010-05-13 US disclosed
US-20100121049-A1 INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORPORATION (US) 2010-05-13 US disclosed
US-7652028-B2 Indenoisoquinolinone analogs and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2010-01-26 US disclosed
US-7652028-B2 Indenoisoquinolinone analogs and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2010-01-26 US disclosed
US-20100004220-A1 Indenoisoquinolinone Analogs and Methods of Use Thereof INOTEK PHARMACEUTICALS CORPORATION 2010-01-07 US disclosed
US-20070049555-A1 Indenoisoquinolinone analogs and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2007-03-01 US disclosed
US-20070049555-A1 Indenoisoquinolinone analogs and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260056855-A1 COST REDUCED HIGH RELIABILITY FAULT TOLERANT COMPUTER ARCHITECTURE KCNN4, OXSR1, INF2 KDM4E 3370/4885LMNA 1516/4885ALOX15 4453/4885
US-12554657-B2 Virtualization-based platform protection technology HPN, POT1, AVPR2 KDM4E 2430/4885LMNA 3988/4885ALOX15 4402/4885
US-12583882-B2 Equatorially modified polymer linked multimers of guansine-3′, 5′-cyclic monophosphates PDE7A, PRKG1, NT5C3B KDM4E 1316/4885LMNA 2067/4885ALOX15 4414/4885
US-20070049555-A1 Indenoisoquinolinone analogs and methods of use thereof TNNI3, IDH2, GLS KDM4E 2660/4885LMNA 407/4885ALOX15 262/4885
US-20250390443-A1 VIRTUALIZATION-BASED PLATFORM PROTECTION TECHNOLOGY HPN, AVPR2, AVPR1A KDM4E 2493/4885LMNA 4061/4885ALOX15 3929/4885
US-20100121049-A1 INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF TNNI3, IDH2, GLS KDM4E 2660/4885LMNA 407/4885ALOX15 262/4885
US-12572378-B2 Secure arbitration mode to build and operate within trust domain extensions INTS9, TIMM9, MAX KDM4E 2043/4885LMNA 834/4885ALOX15 4840/4885
US-20100004220-A1 Indenoisoquinolinone Analogs and Methods of Use Thereof TNNI3, IDH2, GLS KDM4E 2660/4885LMNA 407/4885ALOX15 262/4885
US-20100179140-A1 INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF TNNI3, IDH2, GLS KDM4E 2660/4885LMNA 407/4885ALOX15 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.