SCHEMBL11575792

SCHEMBL11575792

CCOc1ccc(C(=O)c2ccccc2)c(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.63
LMNA P02545 3/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
HPGD P15428 5/20 0.60
ALDH1A1 P00352 4/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
RAB9A P51151 2/20 0.57
HCRTR1 O43613 1/20 0.57
HCRTR2 O43614 1/20 0.57
SRD5A2 P31213 1/20 0.56
MAPT P10636 5/20 0.55
KDM4E B2RXH2 3/20 0.55
ALOX15 P16050 3/20 0.55
RECQL P46063 2/20 0.55
HSD17B10 Q99714 2/20 0.55
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
ALOX12 P18054 1/20 0.53
CHRNA7 P36544 1/20 0.52
POLB P06746 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11573931 0.88 LMNA (0.57) MAPK1LMNAL3MBTL1HPGDSRD5A2
SCHEMBL11807084 0.87 ALDH1A1 (0.56) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL27859781 0.85 GAA (0.68) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL14315506 0.85 SRD5A2 (0.60) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL29633670 0.85 HPGD (0.76) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL561937 0.85 HPGD (0.76) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL17919809 0.85 THRA (0.59) MAPK1LMNAL3MBTL1TSHR
SCHEMBL11576385 0.84 MAPT (0.57) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL28304380 0.84 LMNA (0.52) MAPK1LMNAL3MBTL1HPGDALDH1A1
SCHEMBL10371698 0.84 MAPK1 (0.58) MAPK1LMNAL3MBTL1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed