Biphenyl

Biphenyl

SCHEMBL11575796

C=CCBr.[O].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
TSHR P16473 4/20 0.47
L3MBTL1 Q9Y468 1/20 0.42
MAPK1 P28482 1/20 0.42
PTPN1 P18031 1/20 0.40
GSK3B P49841 1/20 0.40
TRPA1 O75762 1/20 0.38
TAAR1 Q96RJ0 2/20 0.37
MMP9 P14780 1/20 0.37
HSD17B10 Q99714 2/20 0.36
IDH1 O75874 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOTUM Q6P988 1/20 0.36
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27912801 0.97 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1MAPK1PTPN1
Benzene SCHEMBL14645900 0.80 TSHR (0.75) ALDH1A1TSHRTRPA1
Styrene SCHEMBL11407058 0.77 ALDH1A1 (0.70) ALDH1A1TSHRL3MBTL1TRPA1TDP1
Biphenyl SCHEMBL3596635 0.76 ALDH1A1 (0.69) ALDH1A1TSHRMAPK1PTPN1GSK3B
Biphenyl SCHEMBL7803891 0.76 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1MAPK1TAAR1
Biphenyl SCHEMBL16146354 0.76 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1MAPK1TAAR1
Biphenyl SCHEMBL8734478 0.76 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1MAPK1TAAR1
Biphenyl SCHEMBL3258858 0.76 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1TAAR1MMP9
Biphenyl SCHEMBL5324255 0.76 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1MAPK1TAAR1
SCHEMBL1652820 0.75 TDP1 (0.57) ALDH1A1TSHRTRPA1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4170711-A FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES GENERAL ELECTRIC COMPANY (US) 1979-10-09 US disclosed