Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL8310031 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPK1TSHRPTPN1GSK3B | |
| Biphenyl SCHEMBL29008551 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| Biphenyl SCHEMBL1358618 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| SCHEMBL30629023 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| Biphenyl SCHEMBL164 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| Biphenyl SCHEMBL28890607 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| Biphenyl SCHEMBL4002609 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| Biphenyl SCHEMBL2548048 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| SCHEMBL30108088 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 | |
| SCHEMBL29560186 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MAPK1TAAR1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102206208-A | Preparation method for olmensartan medoxomil with low-level impurity | SHANGHAI MODERN PHARMACEUTICAL CO LTD | 2011-10-05 | — | — | CN | disclosed |
| US-20100076200-A1 | Purification of olmesartan medoxomil | HEDVATI LILACH | 2010-03-25 | — | — | US | disclosed |
| US-7528258-B2 | Preparation of olmesartan medoxomil | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2009-05-05 | — | — | US | disclosed |
| EP-1784398-A1 | PURIFICATION OF OLMESARTAN MEDOXOMIL | Teva Pharmaceutical Industries Ltd (IL) | 2007-05-16 | — | — | EP | disclosed |
| US-20070054948-A1 | Purification of olmesartan medoxomil | TEVA PHARMACEUTICALS USA, INC. | 2007-03-08 | — | — | US | disclosed |
| EP-1716138-A1 | PROCESS FOR PREPARING OLMESARTAN MEDOXOMIL AT PH HIGHER THAN 2.5 | Teva Pharmaceutical Industries Ltd (IL) | 2006-11-02 | — | — | EP | disclosed |
| EP-1706401-A1 | PREPARATION OF OLMESARTAN MEDOXOMIL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-10-04 | — | — | EP | disclosed |
| WO-2006073518-A1 | PROCESS FOR PREPARING OLMESARTAN MEDOXOMIL AT PH HIGHER THAN 2.5 | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-07-13 | — | — | WO | disclosed |
| US-20060148870-A1 | Process for preparing olmesartan medoxomil AT pH higher than 2.5 | TEVA PHARMACEUTICALS USA, INC. | 2006-07-06 | — | — | US | disclosed |
| US-20060074117-A1 | Purification of olmesartan medoxomil | TEVA PHARMACEUTICALS USA, INC. | 2006-04-06 | — | — | US | disclosed |
| US-20060069141-A1 | Preparation of olmesartan medoxomil | TEVA PHARMACEUTICALS USA, INC. | 2006-03-30 | — | — | US | disclosed |
| WO-2006029057-A1 | PURIFICATION OF OLMESARTAN MEDOXOMIL | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006029056-A1 | PREPARATION OF OLMESARTAN MEDOXOMIL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-03-16 | — | — | WO | disclosed |
| CN-1219799-C | Preparation method of vinyl polymer whose terminal has functional group | SEKISUI CHEMICAL CO LTD (JP) | 2005-09-21 | — | — | CN | disclosed |
| CN-1495201-A | Preparation method of vinyl polymer whose terminal has functional group | 积水化学工业株式会社 | 2004-05-12 | — | — | CN | disclosed |
| CN-1137907-C | Method for producing vinyl polymer having functional group at terminal, and vinyl polymer having functional group at terminal | 积水化学工业株式会社 | 2004-02-11 | — | — | CN | disclosed |
| CN-1346374-A | Method for producing vinyl polymer having functional group at terminal, and vinyl polymer having functional group at terminal | SEKISUI CHEMICAL CO LTD (JP) | 2002-04-24 | — | — | CN | disclosed |
| US-4420595-A | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1983-12-13 | — | — | US | disclosed |
| EP-0044595-A1 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148870-A1 | Process for preparing olmesartan medoxomil AT pH higher than 2.5 | AGTR2, AGTR1, NOX5 | ALDH1A1 1287/4885MAPK1 519/4885TSHR 4315/4885 |
| US-20070054948-A1 | Purification of olmesartan medoxomil | AGTR2, AGTR1, REN | ALDH1A1 2331/4885MAPK1 1345/4885TSHR 3075/4885 |
| US-20060074117-A1 | Purification of olmesartan medoxomil | AGTR2, AGTR1, REN | ALDH1A1 2182/4885MAPK1 1359/4885TSHR 3396/4885 |
| US-20100076200-A1 | Purification of olmesartan medoxomil | AGTR2, AGTR1, REN | ALDH1A1 2182/4885MAPK1 1359/4885TSHR 3396/4885 |
| US-20060069141-A1 | Preparation of olmesartan medoxomil | AGTR2, CYP4A11, AGTR1 | ALDH1A1 2271/4885MAPK1 859/4885TSHR 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.