Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL11575843

SS.c1ccc2scnc2c1

nearest known ligand 0.91

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.91
HSD17B10 Q99714 3/20 0.91
DYRK1A Q13627 1/20 0.43
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
KDM4E B2RXH2 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
HKDC1 Q2TB90 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RIPK1 Q13546 1/20 0.38
MAPK14 Q16539 1/20 0.38
IDO1 P14902 1/20 0.36
RIPK2 O43353 2/20 0.36
EGFR P00533 1/20 0.36
KDR P35968 1/20 0.36
TGFBR1 P36897 1/20 0.36
RIPK3 Q9Y572 1/20 0.36
APP P05067 1/20 0.35
SYK P43405 1/20 0.35
ADRA2A P08913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL10847268 0.95
Benzo[D]Thiazole SCHEMBL31388426 0.95
Benzo[D]Thiazole SCHEMBL451685 0.95
Benzo[D]Thiazole SCHEMBL8430 0.95
Benzo[D]Thiazole SCHEMBL900814 0.95 ALDH1A1 (1.00) ALDH1A1HSD17B10DYRK1ANPC1RAB9A
Benzo[D]Thiazole SCHEMBL28708292 0.93 ALDH1A1 (0.86) ALDH1A1HSD17B10DYRK1ANPC1RAB9A
Benzo[D]Thiazole SCHEMBL9815307 0.93 ALDH1A1 (0.86) ALDH1A1HSD17B10DYRK1ANPC1RAB9A
Benzo[D]Thiazole SCHEMBL5141991 0.93 ALDH1A1 (0.95) ALDH1A1HSD17B10DYRK1ANPC1RAB9A
Benzo[D]Thiazole SCHEMBL9551908 0.93 ALDH1A1 (0.95) ALDH1A1HSD17B10DYRK1ANPC1RAB9A
Benzo[D]Thiazole SCHEMBL8723619 0.93 ALDH1A1 (0.95) ALDH1A1HSD17B10DYRK1ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116194525-A Reinforced elastomer composition OMYA国际股份公司 2023-05-30 CN disclosed
US-4145240-A CHLOROSULFONATED POLYETHYLENE RUBBER AND HEAT-HARDENABLE MELAMINE RESIN, VULCANIZATION, TEMPORARY SUPPORT PLAMA PLASTIC METALLIC LIMITED (GB) 1979-03-20 US disclosed