⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894891 | 0.97 | GAA (0.41) | — | |
| SCHEMBL8587177 | 0.97 | — | — | |
| SCHEMBL15499989 | 0.92 | — | — | |
| Cetyl Alcohol SCHEMBL28033314 | 0.87 | LMNA (0.54) | — | |
| SCHEMBL4738672 | 0.85 | ALDH1A1 (0.48) | — | |
| SCHEMBL10338832 | 0.82 | ALDH1A1 (0.46) | — | |
| Ethylene Glycol SCHEMBL4725586 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL1828683 | 0.79 | — | — | |
| SCHEMBL30287656 | 0.78 | — | — | |
| Ethylene Glycol SCHEMBL11225967 | 0.77 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383895-A1 | FACTOR VIII WITH EXTENDED HALF-LIFE AND REDUCED LIGAND-BINDING PROPERTIES | Baxalta Incorporated (US) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017096383-A1 | FACTOR VIII WITH EXTENDED HALF-LIFE AND REDUCED LIGAND-BINDING PROPERTIES | BAXALTA INCORPORATED (US) | 2017-06-08 | — | — | WO | disclosed |
| EP-2459226-A2 | GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS | Lipoxen Technologies Limited (GB) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012850-A2 | GLYCOPOLYSIALYLATION OF NON-BLOOD COAGULATION PROTEINS | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |
| WO-2007090793-A1 | NITROOXY-COMPRISING DERIVATIVES OF APRACLONIDINE AND BRIMODNIDINE AS AL PHA2 -ADRENERGIC RECEPTOR AGONISTS | NICOX S.A. (FR) | 2007-08-16 | — | — | WO | disclosed |