⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157589 | 0.92 | — | — | |
| SCHEMBL27894891 | 0.89 | GAA (0.41) | — | |
| SCHEMBL8587177 | 0.89 | — | — | |
| Ethylene Glycol SCHEMBL4725586 | 0.81 | ALDH1A1 (0.43) | — | |
| SCHEMBL1828683 | 0.81 | — | — | |
| SCHEMBL30287656 | 0.81 | — | — | |
| SCHEMBL4738672 | 0.81 | ALDH1A1 (0.48) | — | |
| Cetyl Alcohol SCHEMBL28033314 | 0.79 | LMNA (0.54) | — | |
| Ethylene Glycol SCHEMBL11225967 | 0.79 | ALDH1A1 (0.42) | — | |
| Hydrogen Sulfide SCHEMBL27615479 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4450069-A2 | PROCESSES FOR PREPARING NITROSYLATED PROPANEDIOLS, COMPOSITIONS COMPRISING THE SAME, AND MEDICAL USES THEREOF | Attgeno AB (SE) | 2024-10-23 | — | — | EP | disclosed |
| EP-4157235-A1 | MONO- AND BIS-NITROSYLATED ALKYL POLYOLS FOR THERAPEUTIC USE | Attgeno AB (SE) | 2023-04-05 | — | — | EP | disclosed |
| EP-4157234-A1 | MONO- AND BIS-NITROSYLATED PROPANEDIOLS FOR THERAPEUTIC USE | Attgeno AB (SE) | 2023-04-05 | — | — | EP | disclosed |
| CN-115884757-A | Mononitrosated and bisnitrosated propylene glycols for therapeutic use | 阿特格诺有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115867263-A | Mono-and di-nitrosylated alkyl polyols for therapeutic use | 阿特格诺有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113164427-A | Process for the preparation of nitrosylated propylene glycols, compositions containing them and their medical use | 阿特格诺有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-10034828-B2 | Hair treatment systems and methods using peptides and other compositions | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-10034898-B2 | Methods and systems for treatment of inflammatory diseases with nitric oxide | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-10028994-B2 | Memory or learning improvement using peptide and other compositions | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2018-07-24 | — | — | US | disclosed |
| US-9968634-B2 | Techniques and systems for treatment of neuropathic pain and other indications | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20140079764-A1 | TREATMENT AND PREVENTION OF LEARNING AND MEMORY DISORDERS | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079768-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF OSTEOPOROSIS AND OTHER INDICATIONS | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079761-A1 | SYSTEMS AND METHODS FOR TREATMENT OF ACNE VULGARIS AND OTHER CONDITIONS WITH A TOPICAL NITRIC OXIDE DELIVERY SYSTEM | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079766-A1 | METHODS AND COMPOSITIONS FOR MUSCULAR AND NEUROMUSCULAR DISEASES | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079679-A1 | PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES USING SYSTEMS AND METHODS FOR TRANSDERMAL NITRIC OXIDE DELIVERY | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079762-A1 | TREATMENT OF SKIN AND SOFT TISSUE INFECTION WITH NITRIC OXIDE | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079763-A1 | METHODS AND SYSTEMS FOR TREATMENT OF INFLAMMATORY DISEASES WITH NITRIC OXIDE | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079767-A1 | CANCER TREATMENTS AND COMPOSITIONS FOR USE THEREOF | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140079765-A1 | TECHNIQUES AND SYSTEMS FOR TREATMENT OF NEUROPATHIC PAIN AND OTHER INDICATIONS | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8668937-B2 | Topical nitric oxide systems and methods of use thereof | TRANSDERMAL BIOTECHNOLOGY, INC. (US) | 2014-03-11 | — | — | US | disclosed |