Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665382 | 0.83 | FOLH1 (0.47) | FFAR1LMNAGABBR2GABBR1CYP2C9 | |
| SCHEMBL25152663 | 0.82 | GABBR2 (0.61) | FFAR1LMNAGABBR2GABBR1CYP2C9 | |
| SCHEMBL3928758 | 0.82 | GABBR2 (0.61) | FFAR1LMNAGABBR2GABBR1CYP2C9 | |
| SCHEMBL25152267 | 0.82 | GABBR2 (0.61) | FFAR1LMNAGABBR2GABBR1CYP2C9 | |
| SCHEMBL12197892 | 0.81 | FFAR1 (0.48) | FFAR1LMNAGABBR2GABBR1CYP2C9 | |
| SCHEMBL14487156 | 0.77 | ALDH1A1 (0.53) | CA2CAMK2AFFAR1LMNATSHR | |
| SCHEMBL909093 | 0.76 | CA2 (0.56) | CA2CAMK2AFFAR1LMNACYP2C9 | |
| Hydrochloric Acid SCHEMBL2527629 | 0.74 | CA2 (0.54) | CA2CAMK2AFFAR1LMNACYP2C9 | |
| SCHEMBL10978746 | 0.74 | CA2 (0.54) | CA2CAMK2AFFAR1LMNACYP2C9 | |
| SCHEMBL29248834 | 0.74 | CA2 (0.54) | CA2CAMK2AFFAR1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076838-A | ANTIARTHRITIC, ANALGESICS, ANTIPHLOGISTICS | SANDOZ LTD. (CH) | 1978-02-28 | — | — | US | disclosed |