Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11395178 | 0.87 | TP53 (0.35) | TAS1R3TAS1R1TP53HDAC7HDAC8 | |
| SCHEMBL11601597 | 0.86 | TAS1R3 (0.31) | TAS1R3TAS1R1TP53 | |
| SCHEMBL1780277 | 0.83 | TAS1R3 (0.34) | TAS1R3TAS1R1TP53HDAC7HDAC8 | |
| SCHEMBL11589625 | 0.83 | CA12 (0.30) | — | |
| SCHEMBL9615840 | 0.73 | — | — | |
| SCHEMBL11395193 | 0.72 | LMNA (0.35) | SMN1; SMN2 | |
| SCHEMBL1726872 | 0.71 | SMN1; SMN2 (0.48) | TP53HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL25478475 | 0.70 | TP53 (0.42) | TP53HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL11233882 | 0.70 | TP53 (0.33) | TP53HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL11230767 | 0.70 | TP53 (0.33) | TP53HDAC7HDAC8HDAC6HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104298-A | FROM SULFAMIC ACIDS AND PHOSPHORUS PENTAHALIDES | BASF AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4101571-A | REACTING SULFAMIC ACIDS WITH PHOSGENE | BASF AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |