Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986016 | 0.87 | ALDH1A1 (0.67) | LMNAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL4003436 | 0.85 | LMNA (0.66) | LMNAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL29678332 | 0.85 | LMNA (0.66) | LMNAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL14085811 | 0.85 | ALDH1A1 (0.67) | LMNAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL12720508 | 0.85 | MEN1 (0.80) | LMNAMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL300285 | 0.84 | KMT2A (0.66) | HPGDALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL29554472 | 0.84 | KMT2A (0.66) | HPGDALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4210079 | 0.83 | LMNA (0.64) | LMNAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL31365405 | 0.83 | HDAC3 (0.62) | LMNAHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL7078969 | 0.83 | HDAC3 (0.62) | LMNAHPGDMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |