Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12862548 | 0.72 | SLC6A3 (0.40) | KDM4EHPGDHSD17B10USP2ALDH1A1 | |
| SCHEMBL257133 | 0.72 | NOS1 (0.39) | MAPTKDM4EHSD17B10MAPK1 | |
| SCHEMBL11577320 | 0.71 | TP53 (0.37) | TP53MAPTCACNA2D1KDM4EHPGD | |
| SCHEMBL19256884 | 0.64 | PTGS1 (0.34) | — | |
| SCHEMBL11576182 | 0.62 | CACNA2D1 (0.34) | TP53MAPTCACNA2D1KDM4EHPGD | |
| SCHEMBL19256889 | 0.62 | PTGS1 (0.35) | MAPTKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL24974319 | 0.60 | SLC6A3 (0.37) | — | |
| SCHEMBL2584656 | 0.60 | HPGD (0.39) | TP53MAPTCACNA2D1KDM4EHPGD | |
| SCHEMBL3505082 | 0.60 | SLC6A3 (0.40) | TP53MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL10391843 | 0.60 | KDM4E (0.45) | KDM4EHPGDHSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29843-E | Substituted thiazoles and flavoring processes and products produced thereby | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |