Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257133 | 0.78 | NOS1 (0.39) | PTGS1PTGS2KDM4EMAPK1HSD17B10 | |
| SCHEMBL19256884 | 0.78 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL19256892 | 0.73 | ALDH1A1 (0.30) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9957284 | 0.72 | ALDH1A1 (0.39) | KDM4EHSD17B10SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19256887 | 0.71 | — | — | |
| SCHEMBL10435591 | 0.71 | ALDH1A1 (0.35) | KDM4EMAPK1HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL27449111 | 0.67 | — | — | |
| SCHEMBL11690038 | 0.66 | ALDH1A1 (0.35) | PTGS1PTGS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13700990 | 0.64 | — | — | |
| SCHEMBL5154036 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730449-B2 | Thiazole compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |