Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.58 |
| ▸ | HTR7 | P34969 | 10/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575616 | 0.83 | HTR7 (0.54) | HTR1AHTR7DRD2HTR6CARM1 | |
| SCHEMBL14204163 | 0.81 | LTA4H (0.68) | HTR1AHTR7DRD2HTR6KDM1A | |
| SCHEMBL7725283 | 0.80 | CA12 (0.62) | SIGMAR1CARM1PRMT6 | |
| SCHEMBL7546010 | 0.80 | CARM1 (0.56) | KDM1ASIGMAR1CARM1PRMT6 | |
| SCHEMBL4729810 | 0.78 | LTA4H (0.79) | HTR1AHTR7DRD2HTR6KDM1A | |
| SCHEMBL4729812 | 0.78 | LTA4H (0.79) | HTR1AHTR7DRD2HTR6KDM1A | |
| SCHEMBL17085450 | 0.78 | LTA4H (0.62) | HTR1AHTR7DRD2HTR6KDM1A | |
| SCHEMBL6398998 | 0.77 | LTA4H (0.80) | HTR1AHTR7LTA4HTMEM97SIGMAR1 | |
| SCHEMBL6278104 | 0.77 | LTA4H (0.80) | HTR1AHTR7LTA4HTMEM97SIGMAR1 | |
| SCHEMBL5544791 | 0.77 | LTA4H (0.80) | HTR1AHTR7LTA4HTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29828-E | ANALGESICS, ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1978-11-07 | — | — | US | disclosed |