SCHEMBL11577451

SCHEMBL11577451

O=c1oc(=O)c2ccc1cc2.[CaH2]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.36
CA12 O43570 5/20 0.36
CA9 Q16790 5/20 0.36
TDP1 Q9NUW8 4/20 0.36
LMNA P02545 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
SOST Q9BQB4 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HSD17B3 P37058 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 4/20 0.32
HPGD P15428 4/20 0.32
KDM4E B2RXH2 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110031 0.96 MCL1 (0.38) MCL1CA12CA9TDP1LMNA
SCHEMBL21173972 0.87 TDP1 (0.33) MCL1CA12CA9TDP1LMNA
Ethylene Glycol SCHEMBL10344735 0.82 CA12 (0.36) MCL1CA12CA9TDP1LMNA
SCHEMBL31481273 0.80 ELANE (0.52) TDP1LMNAL3MBTL1ALDH1A1HPGD
SCHEMBL21173933 0.78 HSD17B10 (0.35) MCL1CA12CA9TDP1LMNA
SCHEMBL30525501 0.76 CA12 (0.52) MCL1CA12CA9TDP1LMNA
SCHEMBL31025596 0.74 GPR35 (0.34) ALDH1A1HPGDKDM4EHSD17B10AKR1B1
SCHEMBL10589100 0.74 CA12 (0.50) MCL1CA12CA9TDP1LMNA
SCHEMBL4932054 0.69
SCHEMBL21173950 0.68 ELANE (0.32) KDM4EMAPTELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101523-A POLYETHYLENE TEREPHTHALATE, CALCIUM TEREPHTHALATE ANHYDRIDE PARTICLES MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4096109-A POLYETHYLENE TEREPHTHALATE, INERT PARTICLES MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-20 US claimed
US-4101523-A POLYETHYLENE TEREPHTHALATE, CALCIUM TEREPHTHALATE ANHYDRIDE PARTICLES MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US disclosed
US-4101523-A POLYETHYLENE TEREPHTHALATE, CALCIUM TEREPHTHALATE ANHYDRIDE PARTICLES MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US disclosed
US-4096109-A POLYETHYLENE TEREPHTHALATE, INERT PARTICLES MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-20 US disclosed