Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577489 | 0.92 | HCAR2 (0.42) | HCAR2 | |
| SCHEMBL20550079 | 0.74 | — | — | |
| SCHEMBL7130273 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL10580682 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL43764 | 0.68 | HCAR2 (0.45) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL375029 | 0.68 | HCAR2 (0.45) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL43004 | 0.68 | HCAR2 (0.45) | KEAP1NFE2L2HCAR2 | |
| Cyclohexane SCHEMBL8842743 | 0.67 | ALDH1A1 (0.34) | — | |
| SCHEMBL8014080 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL14118047 | 0.67 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29772-E | IMPACT STRENGTH, CLARITY, WEATHER RESISTANCE | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |