Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577488 | 0.92 | KEAP1 (0.33) | HCAR2 | |
| SCHEMBL642104 | 0.73 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL642105 | 0.73 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL1964699 | 0.73 | HCAR2 (0.54) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Ethane SCHEMBL29288096 | 0.71 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL28920930 | 0.71 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Methane SCHEMBL9860828 | 0.71 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9315123 | 0.71 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL1272868 | 0.71 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL2486319 | 0.71 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29772-E | IMPACT STRENGTH, CLARITY, WEATHER RESISTANCE | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |