SCHEMBL11577699

SCHEMBL11577699

CNCC(O)c1ccc(OCC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
KDM4E B2RXH2 3/20 0.53
CYP2C9 P11712 2/20 0.53
THPO P40225 2/20 0.53
BLM P54132 2/20 0.53
HIF1A Q16665 2/20 0.53
HTR1A P08908 1/20 0.53
NMUR2 Q9GZQ4 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53
ALOX15 P16050 1/20 0.49
ADRB3 P13945 3/20 0.48
ADRB2 P07550 2/20 0.48
CYP1A2 P05177 2/20 0.48
ADRB1 P08588 2/20 0.48
ADRA1D P25100 1/20 0.48
ADRA1A P35348 1/20 0.48
ADRA1B P35368 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8317100 0.81 TDP1 (0.46) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E
SCHEMBL7338995 0.81 HIF1A (0.58) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E
SCHEMBL8379178 0.79 ALDH1A1 (0.48) ALDH1A1TSHRSMN1; SMN2CYP2C9ALOX15
SCHEMBL8379183 0.79 ALDH1A1 (0.48) ALDH1A1TSHRSMN1; SMN2CYP2C9ALOX15
SCHEMBL8320924 0.79 ALDH1A1 (0.57) ALDH1A1TSHRSMN1; SMN2ALOX15ADRB3
SCHEMBL14032606 0.79 ALDH1A1 (0.66) ALDH1A1TSHRSMN1; SMN2ALOX15MAPT
SCHEMBL11575597 0.79 ALDH1A1 (0.57) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E
SCHEMBL6831673 0.78 ALDH1A1 (0.64) ALDH1A1TSHRSMN1; SMN2ALOX15ADRB3
Hydrochloric Acid SCHEMBL9778047 0.78 ALDH1A1 (0.55) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E
SCHEMBL6319835 0.78 ALDH1A1 (0.56) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4108973-A OXIDATION HOFFMANN-LA ROCHE INC. (US) 1978-08-22 US claimed