Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577699 | 0.81 | ALDH1A1 (0.56) | TDP1HIF1AKDM4EALDH1A1THPO | |
| SCHEMBL8958894 | 0.81 | CNR1 (0.53) | ALDH1A1SMN1; SMN2LMNAPTPN1PSEN1 | |
| SCHEMBL9772363 | 0.80 | RAB9A (0.52) | KDM4EALDH1A1PTPN1PSEN1PSEN2 | |
| SCHEMBL18746067 | 0.77 | PTPN1 (0.46) | ALDH1A1SMN1; SMN2PTPN1PSEN1PSEN2 | |
| SCHEMBL8713627 | 0.77 | PSEN1 (0.55) | ALDH1A1SMN1; SMN2LMNAPTPN1PSEN1 | |
| SCHEMBL6970962 | 0.77 | PTPN1 (0.44) | ALDH1A1SMN1; SMN2PTPN1PSEN1PSEN2 | |
| SCHEMBL8379178 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP2C9LMNAADRB2 | |
| SCHEMBL8379183 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP2C9LMNAADRB2 | |
| SCHEMBL198467 | 0.76 | PTPN1 (0.60) | SMN1; SMN2CYP2C9LMNAPTPN1PSEN1 | |
| SCHEMBL111936 | 0.76 | ALDH1A1 (0.66) | TDP1ALDH1A1SMN1; SMN2LMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |