Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11578105 | 0.87 | TSHR (0.54) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL30166972 | 0.78 | MAOB (0.48) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL3015197 | 0.78 | MAOB (0.48) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL10945153 | 0.78 | NR4A1 (0.48) | TSHRMEN1KMT2AMAPTSMN1; SMN2 | |
| Hydrazine SCHEMBL2891714 | 0.75 | MAOB (0.46) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL4029580 | 0.75 | ALDH1A1 (0.47) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL10866211 | 0.75 | ALDH1A1 (0.50) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL11645362 | 0.75 | MTNR1A (0.51) | SMN1; SMN2ALDH1A1GAANPC1AKR1C3 | |
| SCHEMBL14428178 | 0.75 | KMT2A (0.50) | TSHRMAOBMAOAMEN1KMT2A | |
| SCHEMBL4674459 | 0.73 | ALDH1A1 (0.64) | TSHRMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127670-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-28 | — | — | US | disclosed |