SCHEMBL115791

SCHEMBL115791

CP(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.71
HPGD P15428 1/20 0.60
CA2 P00918 1/20 0.55
CA4 P22748 1/20 0.55
CA5A P35218 1/20 0.55
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CFTR P13569 1/20 0.48
GAA P10253 3/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALPG P10696 1/20 0.46
ALOX12 P18054 1/20 0.46
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TSHR P16473 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25435946 0.97 ESR1 (0.68) ESR1HPGDCA2CA4CA5A
Toluene SCHEMBL27848238 0.89 HPGD (0.71) ESR1HPGDCA2CA4CA5A
SCHEMBL28323706 0.89 ESR1 (0.60) ESR1HPGDCA2CA4CA5A
SCHEMBL5159485 0.87 HPGD (0.85) ESR1HPGDCA2CA4CA5A
SCHEMBL20151013 0.87 ESR1 (0.64) ESR1HPGDCA2CA4CA5A
SCHEMBL27664138 0.87 HPGD (0.61) ESR1HPGDCA2CA4CA5A
SCHEMBL27595157 0.84 ESR1 (0.61) ESR1HPGDCA2CA4CA5A
SCHEMBL31247 0.84 ESR1 (0.54) ESR1HPGDCA2CA4CA5A
SCHEMBL10424890 0.83 ESR1 (0.54) ESR1HPGDCA2CA4CA5A
SCHEMBL28448983 0.81 ESR1 (0.52) ESR1HPGDCA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4108706-B1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE SHINETSU CHEMICAL CO (JP) 2025-09-10 EP claimed
CN-119894954-A System and method for enclosing a PFAS 巴斯夫欧洲公司 2025-04-25 CN claimed
WO-2025051294-A1 NANOCRYSTAL PHOTORESIST-FREE PHOTOLITHOGRAPHIC METHOD BASED ON ORGANOPHOSPHORUS LIGAND 南京大学 2025-03-13 WO claimed
CN-118458709-B Porous silicon nitride material doped with hetero elements, and preparation method and application thereof 浙江工业大学 2024-10-18 CN claimed
CN-117420729-B Application of nano crystal based on organophosphorus ligand in optical patterning 南京大学 2024-10-01 CN claimed
CN-115135698-B Process for producing cyclic polysiloxane 信越化学工业株式会社 2024-04-26 CN claimed
CN-117466935-B Synthesis process of silicon-hydrogen-containing cyclosiloxane 山东东岳有机硅材料股份有限公司 2024-04-16 CN claimed
CN-115608359-B Copper catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2024-04-05 CN claimed
WO-2024064691-A1 SYSTEM AND METHOD FOR PFAS CONTAINMENT BASF SE (DE) 2024-03-28 WO claimed
CN-114405542-B Supported magnetic nano metal catalyst and preparation method and application thereof 万华化学集团股份有限公司 2024-02-27 CN claimed
CN-103282345-A Process for preparing substituted isoxazoline compounds and their precursors 4-chloro-, 4-bromo-or 4-iodobenzaldehyde oximes BASF SE 2013-09-04 CN claimed
US-20130225826-A1 Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes BASF SE (DE) 2013-08-29 US claimed
WO-2012059441-A2 METHOD FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS 4-CHLORO, 4-BROMO- OR 4-IODOBENZALDEHYDE OXIMES BASF SE (DE) 2012-05-10 WO claimed
CN-102414202-A Process for preparing substituted isoxazoline compounds and precursors thereof BASF SE 2012-04-11 CN claimed
US-20120059171-A1 Process for Preparing Substituted Isoxazoline Compounds and Their Precursors BASF SE (DE) 2012-03-08 US claimed
EP-2424862-A1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2012-03-07 EP claimed
WO-2010125130-A1 PROCESS FOR PREPARING SUBSTITUTED ISOXAZOLINE COMPOUNDS AND THEIR PRECURSORS BASF SE (DE) 2010-11-04 WO claimed
WO-1996024601-A1 COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE UNIVERSITY COLLEGE DUBLIN (IE) 1996-08-15 WO claimed
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225826-A1 Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes CYP4X1, CYP4B1, AOX1 ESR1 3703/4885HPGD 1654/4885CA2 2236/4885
US-20120059171-A1 Process for Preparing Substituted Isoxazoline Compounds and Their Precursors CYP4X1, CYP3A7, CYP1B1 ESR1 2232/4885HPGD 932/4885CA2 3296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.