SCHEMBL31247

SCHEMBL31247

CP(C)(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.54
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA5A P35218 1/20 0.52
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CFTR P13569 1/20 0.46
GAA P10253 3/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALPG P10696 1/20 0.44
ALOX12 P18054 1/20 0.44
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HPGD P15428 1/20 0.43
TSHR P16473 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28284821 0.97 ESR1 (0.52) ESR1CA2CA4CA5AALDH1A1
SCHEMBL115791 0.84 ESR1 (0.71) ESR1CA2CA4CA5AALDH1A1
SCHEMBL25435946 0.81 ESR1 (0.68) ESR1CA2CA4CA5AALDH1A1
SCHEMBL18892991 0.80 ESR1 (0.43) ESR1CA2CA4CA5AALDH1A1
SCHEMBL28448983 0.79 ESR1 (0.52) ESR1CA2CA4CA5AALDH1A1
SCHEMBL29976023 0.78 HDAC8 (0.46) ESR1CA2CA4CA5AALDH1A1
SCHEMBL19732114 0.77 ESR1 (0.50) ESR1CA2CA4CA5AALDH1A1
SCHEMBL482384 0.77 ESR1 (0.50) ESR1CA2CA4CA5AALDH1A1
SCHEMBL19353458 0.77 CA2 (0.62) ESR1CA2CA4CA5AALDH1A1
SCHEMBL11427765 0.77 ESR1 (0.50) ESR1CA2CA4CA5AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024240118-A1 PREPARATION FOR AND USE OF HETEROARYL DERIVATIVES 广州智睿医药科技有限公司 2024-11-28 WO claimed
CN-119019454-A Preparation and application of heteroaryl derivative 广州智睿医药科技有限公司 2024-11-26 CN claimed
CN-111163922-B Natural rubber mould-free manufacturing method 国家科学技术发展局 2023-03-14 CN claimed
US-20220402948-A1 EGFR INHIBITOR, COMPOSITION AND PREPARATION METHOD THEREFOR BETTA PHARMACEUTICALS CO., LTD. (CN) 2022-12-22 US claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
US-20210020838-A1 COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR AND QUANTUM DOT LIGHT-EMITTING DIODE TCL TECHNOLOGY GROUP CORPORATION (CN) 2021-01-21 US claimed
US-20210020858-A1 COMPOSITE MATERIAL AND QUANTUM DOT LIGHT EMITTING DIODE TCL TECHNOLOGY GROUP CORPORATION (CN) 2021-01-21 US claimed
CN-110885674-A Composite material and preparation method thereof TCL集团股份有限公司 2020-03-17 CN claimed
CN-110890469-A Composite material and preparation method thereof TCL集团股份有限公司 2020-03-17 CN claimed
EP-2403642-B1 METHODS OF USING A SELECTIVE HYDROGENATION CATALYST CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-08-02 EP claimed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 US claimed
US-4066690-A CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-03 US claimed
US-4013715-A PROCESS FOR THE MANUFACTURE OF 2-HALO-ETHANE-PHOSPHONIC ACID DIHALIDES AND VINYL-PHOSPHONIC ACID DIHALIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed
EP-3719042-B1 METHOD FOR PRODUCING STYRENE RESIN AND STYRENE RESIN MOLDED ARTICLE IDEMITSU KOSAN CO (JP) 2026-02-18 EP disclosed
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-07-24 US disclosed
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US disclosed
US-4013715-A PROCESS FOR THE MANUFACTURE OF 2-HALO-ETHANE-PHOSPHONIC ACID DIHALIDES AND VINYL-PHOSPHONIC ACID DIHALIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-22 US disclosed
US-3962326-A CARBOXYLIC ACID OR ANHYDRIDE, PHOSGENE, TRISUBSTITUTED PHOSPHINE OXIDE OR SULFIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3962324-A Process for preparing halogenomethane-phosphonic acid dihalides HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3952099-A MICROBIOCIDE, SUGAR ESTER, SULFOXIDE THE PROCTER & GAMBLE COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal GSDMD, PIGS, GANC ESR1 4082/4885CA2 1062/4885CA4 908/4885
US-20220402948-A1 EGFR INHIBITOR, COMPOSITION AND PREPARATION METHOD THEREFOR EGFR, ERBB2, ERBB3 ESR1 242/4885CA2 2746/4885CA4 2322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.