SCHEMBL11580200

SCHEMBL11580200

O=C(O)CCC1=CC(C(=O)O)CC=C1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.33
FFAR1 O14842 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23095830 0.66
SCHEMBL10280445 0.64 KEAP1 (0.35) KEAP1FFAR1NPSR1
SCHEMBL12064869 0.63
SCHEMBL6093157 0.63 KEAP1 (0.34) KEAP1FFAR1NPSR1
SCHEMBL13149371 0.62 NPSR1 (0.35) KEAP1FFAR1NPSR1
SCHEMBL11580203 0.62 PTGS2 (0.30)
SCHEMBL24612950 0.61 GAA (0.31)
SCHEMBL19072240 0.61 NPSR1 (0.34) KEAP1FFAR1NPSR1
SCHEMBL14047884 0.61 HRH3 (0.30)
SCHEMBL11540278 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4098881-A COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES THE PROCTER & GAMBLE COMPANY (US) 1978-07-04 US disclosed