Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630895 | 0.90 | TDP1 (0.43) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL22129589 | 0.83 | SNCA (0.46) | LMNATSHRSMN1; SMN2KMT2ACYP3A4 | |
| SCHEMBL9318015 | 0.83 | LMNA (0.56) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL1149074 | 0.82 | LMNA (0.47) | LMNAF2AKT1TDP1TSHR | |
| SCHEMBL28631384 | 0.82 | ALDH1A1 (0.50) | LMNATDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28019295 | 0.81 | ALDH1A1 (0.44) | LMNATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL15485653 | 0.81 | LMNA (0.54) | LMNAF2PRSS1CTSGCTRB1 | |
| Water SCHEMBL21440321 | 0.81 | LMNA (0.54) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL27192192 | 0.81 | LMNA (0.54) | LMNAF2PRSS1CTSGCTRB1 | |
| SCHEMBL4647395 | 0.80 | LMNA (0.48) | LMNAF2PRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156666-A | HOMO- OR COPOLYMER OF ETHYLENE OR PROPYLENE, A DEGRADATION PROMOTER AND AN INORGANIC FILLER | SHISEIDO COMPANY, LTD. (JP) | 1979-05-29 | — | — | US | disclosed |