Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 6/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344809 | 0.83 | L3MBTL1 (0.52) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL12411578 | 0.83 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL13329848 | 0.82 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL21059266 | 0.82 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL21049600 | 0.82 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7607420 | 0.81 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL16374745 | 0.80 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10513173 | 0.80 | ENPP2 (0.52) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL5147218 | 0.80 | ENPP2 (0.52) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7028183 | 0.80 | ENPP2 (0.52) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105656-A | PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |