Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.38 |
| ▸ | CA2 | P00918 | 11/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTPRE | P23469 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582025 | 0.84 | HDAC1 (0.41) | CA1CA2CA9POLBCYP1A2 | |
| SCHEMBL11581488 | 0.84 | MAPT (0.38) | CA1CA2CA9F2F10 | |
| SCHEMBL11580526 | 0.84 | MAP2K1 (0.47) | MAP2K2MAP2K1 | |
| SCHEMBL11580550 | 0.84 | CA1 (0.37) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11579615 | 0.84 | KDM4E (0.40) | CA1CA2CA9F2F10 | |
| SCHEMBL11580439 | 0.84 | CYP1A2 (0.43) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11580880 | 0.80 | F10 (0.43) | F10PLAUPLATTSHRCYP1A2 | |
| SCHEMBL11876674 | 0.79 | CA1 (0.37) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11056102 | 0.78 | HTT (0.36) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11265962 | 0.76 | CA12 (0.45) | CA1CA2CA9F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |