Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580382 | 0.84 | CA1 (0.38) | CYP1A2MAP2K1CA1CA2CA9 | |
| SCHEMBL4098881 | 0.84 | RAB9A (0.49) | CYP1A2NPSR1RAB9ANPC1KDM4E | |
| SCHEMBL11579747 | 0.82 | RAB9A (0.51) | CYP1A2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11581052 | 0.82 | MAPK1 (0.51) | CYP1A2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11578653 | 0.82 | KMT2A (0.48) | CYP1A2MAPTKMT2ANPSR1ALOX15 | |
| SCHEMBL11580526 | 0.82 | MAP2K1 (0.47) | MAP2K1 | |
| SCHEMBL11580550 | 0.82 | CA1 (0.37) | MAPTMAP2K1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11878414 | 0.80 | MAPT (0.39) | CYP1A2MAPTMEN1KMT2AMAP2K1 | |
| SCHEMBL11580765 | 0.80 | CYP1A2 (0.36) | CYP1A2NPC1 | |
| SCHEMBL11048648 | 0.79 | HTT (0.43) | MAPTMEN1KMT2AMAP2K1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |