Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPRE | P23469 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580382 | 0.84 | CA1 (0.38) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11578514 | 0.84 | NPC1 (0.43) | CA1CA2CA9KIF11NPC1 | |
| SCHEMBL11580439 | 0.82 | CYP1A2 (0.43) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11579739 | 0.82 | CXCR2 (0.43) | CA1CA2CA9KIF11NPC1 | |
| SCHEMBL11580078 | 0.82 | RAB9A (0.51) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL11581252 | 0.82 | KIF11 (0.42) | CA1CA2CA9KIF11NPC1 | |
| SCHEMBL11580526 | 0.82 | MAP2K1 (0.47) | KIF11MAP2K2MAP2K1 | |
| SCHEMBL11881815 | 0.80 | CA1 (0.36) | CA1CA2CA9KIF11PTPRC | |
| SCHEMBL11051599 | 0.79 | RAB9A (0.39) | CA1CA2CA9PTPRCPTPN2 | |
| SCHEMBL11581488 | 0.79 | MAPT (0.38) | CA1CA2CA9KIF11NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |