Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797847 | 0.77 | NOS3 (0.35) | NOS3NOS2TLR8TLR7 | |
| SCHEMBL23457924 | 0.71 | NOS3 (0.32) | NOS3NOS2 | |
| SCHEMBL13653845 | 0.71 | HEXA (0.41) | NOS3NOS2TLR8TLR7DHFR | |
| SCHEMBL395140 | 0.67 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL7742239 | 0.67 | LMNA (0.38) | NOS3NOS2TLR8TLR7KDM4E | |
| SCHEMBL20756151 | 0.67 | NOS3 (0.34) | NOS3NOS2TLR8TLR7 | |
| SCHEMBL9332413 | 0.67 | TLR8 (0.35) | NOS3NOS2TLR8TLR7 | |
| SCHEMBL18965809 | 0.67 | NOS3 (0.34) | NOS3NOS2TLR8TLR7KDM4E | |
| SCHEMBL6997914 | 0.66 | DHFR (0.45) | NOS3NOS2DHFR | |
| SCHEMBL18675325 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079039-A | POLYBENZIMIDAZOLES, N-HETEROCYCLIC | HORIZONS RESEARCH INCORPORATED (US) | 1978-03-14 | — | — | US | disclosed |
| US-3943125-A | Substituted tetraamino heterocyclic compounds, useful in the preparation of substituted polybenzimidazoles and poly-imidazopyrrolones | HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1976-03-09 | — | — | US | disclosed |