SCHEMBL898951

SCHEMBL898951

O=C(S)c1ccccc1S

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
HDAC8 Q9BY41 1/20 0.65
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA9 Q16790 4/20 0.46
CA12 O43570 3/20 0.46
CA5A P35218 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA7 P43166 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA3 P07451 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 1/20 0.43
SRC P12931 1/20 0.39
MDM4 O15151 2/20 0.38
TP53 P04637 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9522207 0.97 MAPT (0.62) MAPTHDAC8CA1CA2CA9
SCHEMBL1158059 0.83 CA12 (0.55) MAPTHDAC8CA1CA2CA9
SCHEMBL1821914 0.81 MAPT (0.68) MAPTHDAC8CA1CA2CA9
Thiosalicylic Acid SCHEMBL31208541 0.79 MAPT (1.00) MAPTHDAC8CA1CA2CA9
Thiosalicylic Acid SCHEMBL28313023 0.79 MAPT (1.00) MAPTHDAC8CA1CA2CA9
Thiosalicylic Acid SCHEMBL50376 0.79 MAPT (1.00) MAPTHDAC8CA1CA2CA9
Thiosalicylic Acid SCHEMBL629705 0.79 MAPT (1.00) MAPTHDAC8CA1CA2CA9
SCHEMBL477978 0.77 MAPT (0.62) MAPTHDAC8CA1CA2CA9
SCHEMBL31475293 0.77 MAPT (0.62) MAPTHDAC8CA1CA2CA9
SCHEMBL1738490 0.77 MAPT (0.70) MAPTHDAC8CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2866777-A2 REDUCING COMPOSITION COMPRISING AT LEAST ONE SULFUR-CONTAINING REDUCING AGENT, AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE CATIONIC SURFACTANT AND AT LEAST ONE OXYETHYLENATED NONIONIC SURFACTANT L'OREAL (FR) 2015-05-06 EP claimed
EP-2866778-A1 REDUCING COMPOSITION COMPRISING AT LEAST ONE SULFUR-CONTAINING REDUCING AGENT, AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE CATIONIC SURFACTANT AND AT LEAST TWO POLYOXYALKYLENATED NONIONIC SURFACTANTS L'OREAL (FR) 2015-05-06 EP claimed
WO-2014001540-A2 REDUCING COMPOSITION COMPRISING AT LEAST ONE SULFUR-CONTAINING REDUCING AGENT, AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE CATIONIC SURFACTANT AND AT LEAST ONE OXYETHYLENATED NONIONIC SURFACTANT L'OREAL (FR) 2014-01-03 WO claimed
WO-2014001542-A1 REDUCING COMPOSITION COMPRISING AT LEAST ONE SULFUR-CONTAINING REDUCING AGENT, AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE CATIONIC SURFACTANT AND AT LEAST TWO POLYOXYALKYLENATED NONIONIC SURFACTANTS L'OREAL (FR) 2014-01-03 WO claimed
EP-1534690-A1 2-SUBSTITUTED BICYCLIC BENZOHETEROCYCLIC COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS Euro-Celtique S.A. (LU) 2005-06-01 EP claimed
US-20040152696-A1 2-substituted bicyclic benzoheterocyclic compounds and their use as sodium channel blockers EURO-CELTIQUE S.A. 2004-08-05 US claimed
WO-2004013111-A1 2-SUBSTITUTED BICYCLIC BENZOHETEROCYCLIC COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS EURO-CELTIQUE S.A. (LU) 2004-02-12 WO claimed
WO-2025034239-A1 NATURAL FORMULATIONS TO REDUCE CPD LEVELS YALE UNIVERSITY (US) 2025-02-13 WO disclosed
US-11826355-B1 Aspirin-mimetic antioxidants for treatment of age-related cataract LU YANSONG (US) 2023-11-28 US disclosed
US-11826355-B1 Aspirin-mimetic antioxidants for treatment of age-related cataract LU YANSONG (US) 2023-11-28 US disclosed
EP-3873484-B1 NOVEL STING AGONISTS VENENUM BIODESIGN LLC (US) 2023-08-23 EP disclosed
EP-3707151-B1 STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING TAKEDA PHARMACEUTICALS CO (JP) 2022-01-05 EP disclosed
CN-113285024-A Semiconductor device having quantum dots, display device, imaging system, and moving object 佳能株式会社 2021-08-20 CN disclosed
EP-0945450-A1 FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME SHIONOGI & CO., LTD. (JP) 1999-09-29 EP disclosed
US-5807813-A Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 1998-09-15 US disclosed
EP-0859757-A1 DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS Farmak A.S. (CZ) 1998-08-26 EP disclosed
EP-0783032-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-07-09 EP disclosed
WO-1997017325-A1 DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS FARMAK A.S. (CZ) 1997-05-15 WO disclosed
EP-0422888-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1991-04-17 EP disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152696-A1 2-substituted bicyclic benzoheterocyclic compounds and their use as sodium channel blockers CACNA1C, CACNA1D, SCN2B MAPT 1507/4885HDAC8 2110/4885CA1 411/4885
US-11826355-B1 Aspirin-mimetic antioxidants for treatment of age-related cataract AGER, SOD3, CAT MAPT 1162/4885HDAC8 2453/4885CA1 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.