Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583035 | 0.76 | HSD17B1 (0.41) | HPGDHSD17B1HSD17B2RECQLCYP3A4 | |
| SCHEMBL20170484 | 0.75 | HSD17B3 (0.42) | HPGDHSD17B1HSD17B2ALDH1A1CYP1A2 | |
| SCHEMBL21678069 | 0.73 | BAZ2B (0.43) | HPGDHSD17B1RECQLCYP3A4TSHR | |
| SCHEMBL11316146 | 0.73 | ALDH1A1 (0.47) | HPGDRECQLCYP3A4TSHRLMNA | |
| SCHEMBL28305611 | 0.72 | CYP3A4 (0.44) | HPGDRECQLCYP3A4TSHRLMNA | |
| SCHEMBL8956467 | 0.70 | MCL1 (0.47) | HPGDRECQLCYP3A4TSHRLMNA | |
| Methylamine SCHEMBL11580647 | 0.69 | HPGD (0.47) | HPGDRECQLCYP3A4TSHRLMNA | |
| SCHEMBL11672356 | 0.68 | ACHE (0.46) | HPGDRECQLCYP3A4TSHRLMNA | |
| SCHEMBL21185147 | 0.67 | CYP3A4 (0.43) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL11581621 | 0.66 | CYP3A4 (0.58) | HPGDRECQLCYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101576-A | COUPLERS FOR HAIR DYES | L'OREAL (FR) | 1978-07-18 | — | — | US | claimed |
| US-4101576-A | COUPLERS FOR HAIR DYES | L'OREAL (FR) | 1978-07-18 | — | — | US | disclosed |
| US-4101576-A | COUPLERS FOR HAIR DYES | L'OREAL (FR) | 1978-07-18 | — | — | US | disclosed |
| US-4101576-A | COUPLERS FOR HAIR DYES | L'OREAL (FR) | 1978-07-18 | — | — | US | disclosed |