SCHEMBL11580663

SCHEMBL11580663

CC(Cc1ccccc1)NC(=O)Nc1ccccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
LMNA P02545 1/20 0.58
TAS1R3 Q7RTX0 2/20 0.58
TAS1R1 Q7RTX1 2/20 0.58
ANPEP P15144 1/20 0.58
GAA P10253 2/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
KCNQ2 O43526 1/20 0.51
CASR P41180 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
EPHX2 P34913 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11583628 0.89 RAB9A (0.60) NPC1RAB9ALMNAGAAKDM4E
SCHEMBL11580761 0.84 NPC1 (0.69) NPC1RAB9ALMNAANPEPGAA
SCHEMBL6374913 0.83 FPR2 (0.67) TAS1R3TAS1R1ANPEPMEN1KMT2A
SCHEMBL6376178 0.83 FPR2 (0.67) TAS1R3TAS1R1ANPEPMEN1KMT2A
SCHEMBL6374921 0.83 FPR2 (0.67) TAS1R3TAS1R1ANPEPMEN1KMT2A
Benzene SCHEMBL11580668 0.82 TAS1R3 (0.65) NPC1RAB9ALMNATAS1R3TAS1R1
SCHEMBL14654946 0.81 NPC1 (1.00) NPC1RAB9ALMNAGAAMEN1
SCHEMBL11580793 0.81 NPC1 (0.63) NPC1RAB9ALMNAANPEPMEN1
SCHEMBL11580858 0.80 NPC1 (0.77) NPC1RAB9ALMNAGAAMEN1
SCHEMBL11581004 0.80 FPR2 (0.72) NPC1RAB9ALMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4078913-A Herbicidal 3-(2-phenylisopropyl)urea derivatives S.D.S. BIOTECH KABUSHIKI KAISHA, 1978-03-14 US disclosed