Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470766 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11578367 | 0.85 | LMNA (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11581691 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11579417 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11580707 | 0.82 | LMNA (0.38) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11579951 | 0.78 | CNR2 (0.42) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11580004 | 0.77 | CNR2 (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11664740 | 0.76 | LMNA (0.44) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL28047928 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27977100 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3997545-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-12-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |