Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 2/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.39 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8857714 | 0.90 | TP53 (0.58) | TP53LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5299930 | 0.86 | CHRNA7 (0.46) | TP53CHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL5300960 | 0.84 | CHKA (0.56) | LMNAHTTSMN1; SMN2ALDH1A1CHKA | |
| Bromide SCHEMBL5907737 | 0.83 | CYP2D6 (0.49) | CYP2D6ACHE | |
| Hydrochloric Acid SCHEMBL10669507 | 0.82 | ALDH1A1 (0.56) | LMNAHTTSMN1; SMN2ALDH1A1CHKA | |
| Bromide SCHEMBL8857808 | 0.82 | CHKA (0.57) | TP53LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5305122 | 0.81 | LPL (0.41) | TP53LMNAHTTSMN1; SMN2CHKA | |
| SCHEMBL10445050 | 0.81 | CYP2D6 (0.50) | SMN1; SMN2ALDH1A1CYP2D6ALOX12ACHE | |
| Bromide SCHEMBL9265154 | 0.80 | TP53 (0.52) | TP53SMN1; SMN2ALDH1A1ALOX12CHRM2 | |
| Benzene SCHEMBL3223041 | 0.80 | TP53 (0.58) | TP53SMN1; SMN2ALDH1A1ALOX12CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123330-A | Color diffusion transfer process using benzyl alcohol and derivatives thereof | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1978-10-31 | — | — | US | disclosed |