Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL11580912

Cc1ccccc1Sc1ccccc1C.S

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 4/20 0.50
HTR3A P46098 4/20 0.50
ACHE P22303 2/20 0.50
HAO1 Q9UJM8 1/20 0.50
TSHR P16473 1/20 0.50
AR P10275 2/20 0.48
IDO1 P14902 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 2/20 0.39
NOTUM Q6P988 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MCHR1 Q99705 1/20 0.38
ICAM1 P05362 1/20 0.38
SELE P16581 1/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576094 0.97 ACHE (0.53) HTR1AHTR3AACHEHAO1TSHR
SCHEMBL15906499 0.94 HTR1A (0.50) HTR1AHTR3AACHEHAO1TSHR
Phosphine SCHEMBL29157942 0.94 HTR1A (0.50) HTR1AHTR3AACHEHAO1TSHR
SCHEMBL29031117 0.94 HTR1A (0.55) HTR1AHTR3AACHEHAO1TSHR
Cyanide SCHEMBL8000324 0.89 AR (0.50) HTR1AHTR3AACHEHAO1TSHR
SCHEMBL9488937 0.85 HTR1A (0.53) HTR1AHTR3AACHEHAO1TSHR
Bicarbonate SCHEMBL31082134 0.85 L3MBTL1 (0.45) HTR1AHTR3AACHEHAO1TSHR
SCHEMBL9488226 0.83 HAO1 (0.47) HTR1AHTR3AACHEHAO1TSHR
SCHEMBL17301730 0.83 L3MBTL1 (0.47) HTR1AHTR3AACHEHAO1TSHR
SCHEMBL3859717 0.83 CYP3A4 (0.52) HTR1AHTR3AHAO1ARALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104220466-B For the method preparing polydiene 株式会社普利司通 2016-09-21 CN disclosed
US-4082808-A ANTIOXIDANTS, INTERMEDIATES FOR POLYESTERS, POLYCARBONATES, EPOXY RESINS GENERAL ELECTRIC COMPANY (US) 1978-04-04 US disclosed
US-3953519-A BASES, EPOXY COMPOUNDS, OLEFINS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed