Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881281 | 0.86 | LMNA (0.44) | HTR1ALMNAALDH1A1NR1H2NR1H3 | |
| SCHEMBL6882742 | 0.84 | LMNA (0.40) | HTR1ALMNAALDH1A1TP53NR1H2 | |
| SCHEMBL6879939 | 0.83 | KCNH2 (0.42) | HTR1ALMNAALDH1A1TP53NR1H2 | |
| SCHEMBL6880657 | 0.82 | HTR1A (0.46) | HTR1ACA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL387883 | 0.81 | ALDH1A1 (0.42) | HTR1ALMNACA1CA2ALDH1A1 | |
| SCHEMBL10333062 | 0.81 | ALDH1A1 (0.42) | HTR1ALMNACA1CA2ALDH1A1 | |
| SCHEMBL6264458 | 0.79 | CYP1A2 (0.41) | HTR1ALMNACA1CA2TSHR | |
| SCHEMBL6884297 | 0.79 | ALDH1A1 (0.35) | HTR1ALMNAALDH1A1 | |
| SCHEMBL30525531 | 0.78 | LMNA (0.47) | HTR1ALMNAALDH1A1NR1H2NR1H3 | |
| SCHEMBL1836555 | 0.78 | LMNA (0.47) | HTR1ALMNAALDH1A1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101541-A | DYES FOR POLYESTERS OR POLYPROPYLENE | CIBA-GEIGY CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4083847-A | Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-3987026-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |