Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748444 | 0.88 | MAOB (0.40) | MAOBGUSBERN1MAPTCYP3A4 | |
| SCHEMBL11582017 | 0.84 | MAOB (0.46) | MAOBESR1ESR2MAPTCYP3A4 | |
| SCHEMBL11584209 | 0.84 | LMNA (0.43) | MAOBESR1ESR2MAPTCYP3A4 | |
| SCHEMBL28682144 | 0.77 | TRPV4 (0.46) | ALDH1A1MEN1KMT2AFLT1FLT4 | |
| SCHEMBL11741371 | 0.75 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23554329 | 0.75 | MAOB (0.53) | MAOBESR1ESR2MAPTCYP3A4 | |
| SCHEMBL7935399 | 0.72 | MAPK1 (0.46) | MAOBESR1ESR2MAPTCYP3A4 | |
| SCHEMBL11743909 | 0.72 | MAOB (0.42) | MAOBESR1ESR2MAPTCYP3A4 | |
| SCHEMBL10537822 | 0.69 | TSHR (0.41) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL3192396 | 0.68 | MAOB (0.48) | MAOBESR1ESR2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066619-A | STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1978-01-03 | — | — | US | claimed |