Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.55 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.55 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443993 | 0.86 | PSMB9 (0.54) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL31122219 | 0.83 | CALCRL (0.49) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL2195454 | 0.82 | OPRD1 (0.55) | PSMB9OPRD1OPRK1REN | |
| SCHEMBL30289679 | 0.82 | SLC6A2 (0.58) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL30001593 | 0.82 | SLC6A2 (0.57) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL30149883 | 0.81 | CALCRL (0.56) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL31323239 | 0.81 | CALCRL (0.56) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL31191391 | 0.81 | OPRD1 (0.53) | CALCRLRAMP1OPRM1OPRD1OPRK1 | |
| SCHEMBL31670606 | 0.81 | ACE (0.49) | CALCRLPSMB9RAMP1OPRM1OPRD1 | |
| SCHEMBL22623411 | 0.81 | XIAP (0.62) | CALCRLOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102877-A | REACTION OF AN OLIGOPEPTIDE WITH ISOPROPYLCARBODIIMIDE BOND TO POLYSTYRENE | MERCK & CO., INC. (US) | 1978-07-25 | — | — | US | claimed |
| US-4102877-A | REACTION OF AN OLIGOPEPTIDE WITH ISOPROPYLCARBODIIMIDE BOND TO POLYSTYRENE | MERCK & CO., INC. (US) | 1978-07-25 | — | — | US | disclosed |