SCHEMBL31122219

N[C@@H](CCC(=O)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	CALCRL	Q16602	3/20	0.49

▸	OPRM1	P35372	3/20	0.48

▸	OPRD1	P41143	3/20	0.48

▸	ACE	P12821	2/20	0.48

▸	RAMP1	O60894	1/20	0.47

▸	OPRK1	P41145	1/20	0.47

▸	PSMB9	P28065	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31122220	0.87	PSMB9 (0.46)	CALCRLACEPSMB9
SCHEMBL29579276	0.86	CALCRL (0.52)	CALCRLOPRM1OPRD1RAMP1OPRK1
SCHEMBL29579416	0.85	CALCRL (0.54)	CALCRLOPRM1OPRD1RAMP1OPRK1
SCHEMBL29579573	0.85	CALCRL (0.61)	CALCRLOPRM1OPRD1RAMP1OPRK1
SCHEMBL31694408	0.85	F2 (0.58)	CALCRLOPRM1OPRD1ACERAMP1
SCHEMBL30001593	0.84	SLC6A2 (0.57)	CALCRLOPRM1OPRD1ACERAMP1
SCHEMBL30456567	0.83	OPRM1 (0.54)	CALCRLOPRM1OPRD1OPRK1
SCHEMBL30431697	0.83	F2 (0.45)	ACE
SCHEMBL30443993	0.83	PSMB9 (0.54)	CALCRLOPRM1OPRD1RAMP1OPRK1
SCHEMBL11582363	0.83	CALCRL (0.55)	CALCRLOPRM1OPRD1RAMP1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-118403146-A	Application of polypeptide PEP-Z-2 in preparation of medicines for treating kidney fibrosis	中国医学科学院药物研究所	2024-07-30	—	—	CN	claimed
CN-118403146-A	Application of polypeptide PEP-Z-2 in preparation of medicines for treating kidney fibrosis	中国医学科学院药物研究所	2024-07-30	—	—	CN	disclosed