Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583186 | 0.95 | ALDH1A1 (0.50) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 | |
| SCHEMBL11582373 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 | |
| SCHEMBL6062140 | 0.78 | LMNA (0.49) | ALDH1A1MAPTTSHRRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10730163 | 0.77 | LMNA (0.50) | ALDH1A1MAPTTSHRRAB9ANPC1 | |
| SCHEMBL14830566 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 | |
| Iodomethane SCHEMBL11581375 | 0.76 | LMNA (0.47) | ALDH1A1MAPTTSHRRAB9ANPC1 | |
| SCHEMBL11583609 | 0.75 | LMNA (0.46) | ALDH1A1MAPTTSHRRAB9ANPC1 | |
| SCHEMBL11230342 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 | |
| SCHEMBL9885857 | 0.70 | ALDH1A1 (0.61) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL6552884 | 0.70 | LMNA (0.49) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069309-A | CATIONIC P-AMINOBENZOATE ESTERS OF SUBSTITUTED AMINO ALKANOLS | AVON PRODUCTS, INC. (US) | 1978-01-17 | — | — | US | disclosed |