SCHEMBL11583293

SCHEMBL11583293

COc1cc(NS(=O)(=O)c2ccccc2)ccc1N

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.63
FFAR4 Q5NUL3 4/20 0.62
HTR6 P50406 3/20 0.62
LMNA P02545 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
HTT P42858 2/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
KDM1A O60341 1/20 0.57
KEAP1 Q14145 1/20 0.55
CYP17A1 P05093 2/20 0.55
CA12 O43570 1/20 0.55
CA9 Q16790 1/20 0.55
PGR P06401 1/20 0.52
ALOX15 P16050 1/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 2/20 0.51
PKM P14618 2/20 0.51
HPGD P15428 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11048890 0.99 MAPT (0.61) MAPTFFAR4HTR6LMNASMN1; SMN2
SCHEMBL399122 0.86 LMNA (0.77) HTR6LMNASMN1; SMN2HTTMEN1
SCHEMBL10947961 0.85 CA12 (0.76) MAPTLMNASMN1; SMN2HTTMEN1
SCHEMBL8589428 0.81 FFAR4 (0.73) MAPTFFAR4HTR6LMNASMN1; SMN2
SCHEMBL6140448 0.81 SMN1; SMN2 (0.57) HTR6LMNASMN1; SMN2HTTMEN1
SCHEMBL6073370 0.80 CA12 (0.59) MAPTHTR6LMNASMN1; SMN2HTT
SCHEMBL10572974 0.80 FFAR4 (0.68) FFAR4HTR6LMNASMN1; SMN2HTT
SCHEMBL2446173 0.80 MAPT (0.55) MAPTLMNASMN1; SMN2HTTKMT2A
SCHEMBL9045758 0.79 LMNA (0.63) MAPTHTR6LMNASMN1; SMN2HTT
SCHEMBL7171823 0.79 HTR6 (0.62) MAPTHTR6LMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4097278-A COBALT/III/ COMPLEX OXIDIZER, PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1978-06-27 US disclosed