Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399122 | 0.86 | LMNA (0.77) | LMNAMEN1KMT2APKMHTR6 | |
| SCHEMBL9045755 | 0.85 | CA12 (0.76) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL7171823 | 0.82 | HTR6 (0.62) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL3409664 | 0.82 | HTR6 (0.66) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL29561554 | 0.80 | ALDH1A1 (0.73) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL29561902 | 0.80 | ALDH1A1 (0.66) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL14880400 | 0.80 | LMNA (0.56) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL11583293 | 0.79 | MAPT (0.63) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL29561401 | 0.79 | ALDH1A1 (0.65) | LMNAMEN1KMT2AMAPTPKM | |
| SCHEMBL29561116 | 0.79 | LMNA (0.69) | LMNAMEN1KMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |