Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583246 | 0.88 | MAPT (0.54) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11584035 | 0.87 | LMNA (0.47) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11583837 | 0.86 | S1PR3 (0.46) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11585100 | 0.86 | KDM4E (0.51) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11585598 | 0.86 | ALDH1A1 (0.46) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11583633 | 0.85 | S1PR3 (0.44) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11585131 | 0.85 | KDM4E (0.44) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11583353 | 0.85 | ALDH1A1 (0.44) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11585603 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10PRSS1 | |
| SCHEMBL11583279 | 0.81 | F2 (0.51) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101551-A | WATER INSOLUBILITY, AFFINITY FOR POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |