Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582903 | 0.89 | ALDH1A1 (0.48) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11583826 | 0.88 | MAPT (0.47) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11585100 | 0.87 | KDM4E (0.51) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11582677 | 0.86 | ALDH1A1 (0.48) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11586538 | 0.85 | MAPT (0.49) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11584073 | 0.83 | KDM4E (0.48) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11586606 | 0.83 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29290485 | 0.82 | ALDH1A1 (0.56) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11583641 | 0.81 | KMT2A (0.52) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL11585187 | 0.81 | KMT2A (0.47) | MAPTPOLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101551-A | WATER INSOLUBILITY, AFFINITY FOR POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |