SCHEMBL1158403

SCHEMBL1158403

CCCCC(Cl)(Cl)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.41
ALDH1A1 P00352 4/20 0.39
AKR1B1 P15121 1/20 0.39
TP53 P04637 1/20 0.39
ALOX15 P16050 2/20 0.38
MAPT P10636 1/20 0.37
GPR84 Q9NQS5 6/20 0.37
PPARG P37231 6/20 0.37
PPARD Q03181 6/20 0.37
PPARA Q07869 6/20 0.37
HDAC11 Q96DB2 5/20 0.37
TSHR P16473 4/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37
PTPN1 P18031 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
MEN1 O00255 1/20 0.37
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2207815 0.93 FDPS (0.43) FDPSALDH1A1AKR1B1ALOX15GPR84
SCHEMBL8464966 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL7617795 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL249486 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL3284980 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL8466412 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL658156 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL7619946 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
SCHEMBL7623878 0.91 SMPD1 (0.45) FDPSALDH1A1ALOX15GPR84PPARG
Ammonia Solution, Strong SCHEMBL28996637 0.89 SMPD1 (0.44) FDPSALDH1A1ALOX15GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9283199-B2 Halogenated aliphatic carboxylic acids, oligomers and/or polymers thereof and their use in devitalizing external and internal neoplasms CIMAS LIMITED (CY) 2016-03-15 US disclosed
US-20160067198-A1 HALOGENATED ALIPHATIC CARBOXYLIC ACIDS, OLIGOMERS AND/OR POLYMERS THEREOF AND THEIR USE IN DEVITALIZING EXTERNAL AND INTERNAL NEOPLASMS CIMAS LIMITED (CY) 2016-03-10 US disclosed
CN-101564925-B High barrier laminated body MITSUBISHI GAS CHEMICAL CO 2014-03-19 CN disclosed
EP-1603932-B1 METHODS AND COMPOSITIONS FOR THE ENZYMATIC SYNTHESIS OF GANGLIOSIDES SENEB BIOSCIENCES INC (US) 2012-10-03 EP disclosed
CN-102695503-A Halogenated aliphatic carboxylic acids, oligomers and/or polymers thereof and their use for inactivating external and internal neoplasias MARDI MEDICINES LTD 2012-09-26 CN disclosed
EP-2440198-A2 HALOGENATED ALIPHATIC CARBOXYLIC ACIDS, OLIGOMERS AND/OR POLYMERS THEREOF AND THEIR USE IN DEVITALIZING EXTERNAL AND INTERNAL NEOPLASMS Mardi Medicines Ltd. (IL) 2012-04-18 EP disclosed
US-20110052641-A1 HALOGENATED ALIPHATIC CARBOXYLIC ACIDS, OLIGOMERS AND/OR POLYMERS THEREOF AND THEIR USE IN DEVITALIZING EXTERNAL AND INTERNAL NEOPLASMS MARDI MEDICINES LTD. (IL) 2011-03-03 US disclosed
US-7888331-B2 Ganglioside compositions and methods of use SENEB BIOSCIENCES, INC. (US) 2011-02-15 US disclosed
WO-2010143188-A2 HALOGENATED ALIPHATIC CARBOXYLIC ACIDS, OLIGOMERS AND/OR POLYMERS THEREOF AND THEIR USE IN DEVITALIZING EXTERNAL AND INTERNAL NEOPLASMS MARDI MEDICINES LTD. (IL) 2010-12-16 WO disclosed
CN-101564925-A High barrier laminated body MITSUBISHI GAS CHEMICAL CO (JP) 2009-10-28 CN disclosed
US-5519007-A ENZYME INHIBITORS OF KINASES FOR NERVOUS SYSTEM INHIBITORS FIDIA, S.P.A. (IT) 1996-05-21 US disclosed
EP-0373039-B1 New lysoganglioside derivatives FIDIA SPA (IT) 1994-04-06 EP disclosed
EP-0410883-A2 Di-lysogangliosides derivatives FIDIA S.p.A. (IT) 1991-01-30 EP disclosed
EP-0208617-B1 CONTROLLED DRUG DEVICE AND PROCESS FOR CATALYSING THE EROSION OF AN ACID LABILE POLYMER MERCK & CO. INC. (US) 1990-09-26 EP disclosed
EP-0373038-A2 New lysosphingolipid derivatives FIDIA S.p.A. (IT) 1990-06-13 EP disclosed
EP-0373039-A2 New lysoganglioside derivatives FIDIA S.p.A. (IT) 1990-06-13 EP disclosed
EP-0208617-A1 Controlled drug device and process for catalysing the erosion of an acid labile polymer MERCK & CO. INC. (US) 1987-01-14 EP disclosed
US-4076911-A PALLADIUM CYANIDE CATALYST UNION OIL COMPANY OF CALIFORNIA (US) 1978-02-28 US disclosed
US-4009203-A REACTION PRODUCT OF TIN HALIDE WITH A CARBOXYLIC ACID AS CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-02-22 US disclosed
US-4007222-A Process for the production of 2-chlorocaproic acids DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160067198-A1 HALOGENATED ALIPHATIC CARBOXYLIC ACIDS, OLIGOMERS AND/OR POLYMERS THEREOF AND THEIR USE IN DEVITALIZING EXTERNAL AND INTERNAL NEOPLASMS CCR10, PBK, CCR3 FDPS 3090/4885ALDH1A1 1008/4885AKR1B1 1741/4885
US-20110052641-A1 HALOGENATED ALIPHATIC CARBOXYLIC ACIDS, OLIGOMERS AND/OR POLYMERS THEREOF AND THEIR USE IN DEVITALIZING EXTERNAL AND INTERNAL NEOPLASMS CCR10, PBK, CCR3 FDPS 3090/4885ALDH1A1 1008/4885AKR1B1 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.