Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 4/20 | 0.58 |
| ▸ | HRH1 known ✓ | P35367 | 4/20 | 0.58 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 3/20 | 0.49 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.42 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.42 |
| ▸ | SCN1A known ✓ | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A known ✓ | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A known ✓ | Q9NY46 | 2/20 | 0.42 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.42 |
| ▸ | HRH2 known ✓ | P25021 | 1/20 | 0.42 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4374402 | 0.85 | HTR2A (0.64) | HTR2AHRH1SIGMAR1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL11755782 | 0.84 | HTR2A (0.81) | HTR2AHRH1SIGMAR1LMNAKDM4E | |
| SCHEMBL7326678 | 0.83 | HTR2A (0.67) | HTR2AHRH1SIGMAR1LMNAKDM4E | |
| SCHEMBL4301966 | 0.83 | HTR2A (0.67) | HTR2AHRH1SIGMAR1LMNAKDM4E | |
| SCHEMBL22042223 | 0.81 | TSHR (0.50) | HTR2AHRH1SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL11738250 | 0.81 | UTS2R (0.43) | LMNASMN1; SMN2HTTCYP2D6 | |
| SCHEMBL11584246 | 0.80 | HTR2A (0.88) | HTR2AHRH1SIGMAR1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL11780058 | 0.78 | SLC6A4 (0.42) | HTR2AHRH1LMNAKDM4EMAPK1 | |
| SCHEMBL11780527 | 0.78 | HTR2A (0.45) | HTR2ASIGMAR1OPRM1OPRK1KCNH2 | |
| SCHEMBL10694479 | 0.78 | HTR2A (0.45) | HTR2ASIGMAR1OPRM1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312565-B2 | Low-VOC cleaning substrates and compositions comprising an eo-po block copolymer non-ionic surfactant | THE CLOROX COMPANY (US) | 2025-05-27 | — | — | US | disclosed |
| US-20240263104-A1 | LOW-VOC CLEANING SUBSTRATES AND COMPOSITIONS | THE CLOROX COMPANY | 2024-08-08 | — | — | US | disclosed |
| US-20240066162-A1 | A NONWOVEN DECONTAMINATION WIPE COMPRISING A SMALL DIAMETER FIBER | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2024-02-29 | — | — | US | disclosed |
| EP-4307981-A1 | A NONWOVEN DECONTAMINATION WIPE COMPRISING A SMALL DIAMETER FIBER | 3M Innovative Properties Company (US) | 2024-01-24 | — | — | EP | disclosed |
| US-20230034034-A1 | LOW-VOC CLEANING SUBSTRATES AND COMPOSITIONS | THE CLOROX COMPANY | 2023-02-02 | — | — | US | disclosed |
| US-11485937-B2 | Low-VOC cleaning substrates and compositions comprising a quat and solvent mixture | THE CLOROX COMPANY (US) | 2022-11-01 | — | — | US | disclosed |
| WO-2022195368-A1 | A NONWOVEN DECONTAMINATION WIPE COMPRISING A SMALL DIAMETER FIBER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-09-22 | — | — | WO | disclosed |
| US-20210009928-A1 | LOW-VOC CLEANING SUBSTRATES AND COMPOSITIONS | THE CLOROX COMPANY | 2021-01-14 | — | — | US | disclosed |
| US-10822576-B2 | Low-VOC cleaning substrates and compositions comprising a mixed ethoxy/propoxy alcohol or fatty acid | THE CLOROX COMPANY (US) | 2020-11-03 | — | — | US | disclosed |
| US-10822575-B2 | Low-VOC cleaning substrates and compositions containing a quaternary ammonium compound | THE CLOROX COMPANY (US) | 2020-11-03 | — | — | US | disclosed |
| EP-1419229-A1 | IMPROVED CLEANING COMPOSITION | The Clorox Company (US) | 2004-05-19 | — | — | EP | disclosed |
| US-6673761-B2 | CLEANING COMPOUNDS USED INDEPENDENTLY OR WITH ABSORBER MATERIALS, COMPRISING ANTISEPTIC MIXTURES OF SURFACTANTS, SOLVENTS, WATER, AMMONIUM COMPOUNDS, CITRIC ACID SALTS AND DETERGENTS | THE CLOROX COMPANY | 2004-01-06 | — | — | US | disclosed |
| US-20030216273-A1 | Bactericidal cleaning wipe | THE CLOROX COMPANY, A DELAWARE CORPORATION | 2003-11-20 | — | — | US | disclosed |
| US-20030148917-A1 | Bactericidal cleaning wipe | THE CLOROX COMPANY | 2003-08-07 | — | — | US | disclosed |
| US-20030109411-A1 | Bactericidal cleaning wipe | THE CLOROX COMPANY, A DELAWARE CORPORATION | 2003-06-12 | — | — | US | disclosed |
| US-20030100465-A1 | For cleaning hard surfaces | THE CLOROX COMPANY, A DELAWARE CORPORATION | 2003-05-29 | — | — | US | disclosed |
| WO-2003018732-A1 | IMPROVED CLEANING COMPOSITION | THE CLOROX COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20020183233-A1 | Bactericidal cleaning wipe | THE CLOROX COMPANY, DELAWARE CORPORATION | 2002-12-05 | — | — | US | disclosed |
| WO-2002048296-A2 | BACTERICIDAL CLEANING WIPE | THE CLOROX COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-5403505-A | An antiseptic concentrate solution comprising a polyamides or polyamideether copolymers, a quaternary ammonium, a phenol, a biguanide and a quaternary phosphonium compounds; stability, water solubility; microbiocides | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009928-A1 | LOW-VOC CLEANING SUBSTRATES AND COMPOSITIONS | SMURF1, VCL, SMURF2 | HTR2A 1761/4885HRH1 593/4885SIGMAR1 756/4885 |
| US-10822575-B2 | Low-VOC cleaning substrates and compositions containing a quaternary ammonium compound | SMURF1, SUMO1, VDAC1 | HTR2A 2026/4885HRH1 875/4885SIGMAR1 896/4885 |
| US-11485937-B2 | Low-VOC cleaning substrates and compositions comprising a quat and solvent mixture | SMURF1, SMURF2, SUMO1 | HTR2A 687/4885HRH1 1400/4885SIGMAR1 912/4885 |
| US-20240263104-A1 | LOW-VOC CLEANING SUBSTRATES AND COMPOSITIONS | SMURF1, VCL, SMURF2 | HTR2A 1761/4885HRH1 593/4885SIGMAR1 756/4885 |
| US-20230034034-A1 | LOW-VOC CLEANING SUBSTRATES AND COMPOSITIONS | SMURF1, VCL, SMURF2 | HTR2A 1761/4885HRH1 593/4885SIGMAR1 756/4885 |
| US-10822576-B2 | Low-VOC cleaning substrates and compositions comprising a mixed ethoxy/propoxy alcohol or fatty acid | SMURF1, SMURF2, VCL | HTR2A 802/4885HRH1 1048/4885SIGMAR1 523/4885 |
| US-12312565-B2 | Low-VOC cleaning substrates and compositions comprising an eo-po block copolymer non-ionic surfactant | VDAC1, RAB5IF, VCL | HTR2A 2609/4885HRH1 1197/4885SIGMAR1 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.