Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587339 | 1.00 | ALDH1A1 (0.73) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11587336 | 1.00 | ALDH1A1 (0.73) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11585026 | 1.00 | ALDH1A1 (0.73) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11586739 | 0.90 | DRD2 (0.61) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11586741 | 0.90 | DRD2 (0.61) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11707675 | 0.88 | PTGS2 (0.71) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11697696 | 0.88 | MAPT (0.71) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL11697686 | 0.88 | MAPT (0.71) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL10819058 | 0.88 | PTGS2 (0.86) | ALDH1A1MAPTHSD17B10KMT2ATDP1 | |
| SCHEMBL10819055 | 0.88 | PTGS2 (0.86) | ALDH1A1MAPTHSD17B10KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110534-A | PROCESS FOR THE PREPARATION OF 3-VINYL AND SUBSTITUTED VINYL CEPHALOSPORINS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-29 | — | — | US | claimed |
| US-4110534-A | PROCESS FOR THE PREPARATION OF 3-VINYL AND SUBSTITUTED VINYL CEPHALOSPORINS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4107431-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |