SCHEMBL11587410

SCHEMBL11587410

CC(C)Oc1cccc(NC(=O)c2ccccc2Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.71
ALDH1A1 P00352 6/20 0.71
MEN1 O00255 5/20 0.71
MAPT P10636 5/20 0.71
LMNA P02545 1/20 0.71
ALOX12 P18054 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
KCNK3 O14649 3/20 0.62
KCNK9 Q9NPC2 3/20 0.62
RAB9A P51151 3/20 0.60
F2R P25116 1/20 0.59
PLAU P00749 1/20 0.56
NPSR1 Q6W5P4 1/20 0.55
NPC1 O15118 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11590385 0.87 KMT2A (0.83) KMT2AALDH1A1MEN1MAPTSMN1; SMN2
Mepronil SCHEMBL29453871 0.84 KCNK3 (0.67) KMT2AALDH1A1MEN1MAPTSMN1; SMN2
Mepronil SCHEMBL30731287 0.84 KCNK3 (0.67) KMT2AALDH1A1MEN1MAPTSMN1; SMN2
Mepronil SCHEMBL20522512 0.84 KCNK3 (0.67) KMT2AALDH1A1MEN1MAPTSMN1; SMN2
Mepronil SCHEMBL18447 0.84 KCNK3 (0.67) KMT2AALDH1A1MEN1MAPTSMN1; SMN2
SCHEMBL11458980 0.83 KMT2A (0.60) KMT2AALDH1A1MEN1MAPTLMNA
SCHEMBL11591396 0.83 NPC1 (0.78) KMT2AKCNK3KCNK9RAB9AF2R
SCHEMBL7667058 0.83 FADS1 (0.69) KMT2AALDH1A1MEN1MAPTLMNA
Mepronil SCHEMBL6429840 0.83 KCNK3 (0.61) KMT2AALDH1A1MEN1MAPTLMNA
SCHEMBL1811042 0.82 KCNK3 (0.60) KMT2AALDH1A1MEN1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4123554-A Fungicidal and germicidal benzanilides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1978-10-31 US disclosed